Analysis of bulk sample of salicylic acid by application of hydrotropic solubilization method

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Analysis of Bulk Sample of Salicylic Acid by Application of Hydrotropic Solubilization Method

In the present investigation, the poorly water-soluble drug, salicylic acid has been solubilized using 0.5 M ibuprofen sodium and 2.0 M sodium salicylate solution as hydrotropic agents for the titrimetric analysis precluding the use of organic solvents. Both hydrotropes are economic and pollution-free. The mean percent estimation of salicylic acid estimated in bulk sample by Indian Pharmacopoei...

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2008

ISSN: 0250-474X

DOI: 10.4103/0250-474x.49135